著 書

H.Iwaki, Y.Hasegawa, M.Teraoka, T.Tokuyama, L.Bernard, and P.C.K.Lau. 2003.
Cyclohexanol biodegradation genes: A pathway of opportunities, 80-92.
In R.A.Gross and H.N.Cheng (eds.), ACS Symposium Series 840, Biocatalysis in Polymer Science. American Chemical Society Press.
 


学術論文
Mirza IA, Yachnin BJ, Wang S, Grosse S, Bergeron H, Imura A, Iwaki H, Hasegawa Y, Lau PC, Berghuis AM.
Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor.
J. Am. Chem. Soc. 131(25):8848-8854 (2009)


H. Iwaki, E. Nakai, S. Nakamura, Y. Hasegawa

Isolation and characterization of new cyclohexylacetic acid-degrading bacteria.
Curr. Microbiol. 57(2):
107-110 (2008)

H. Iwaki, T. Zhang, Y. Hasegawa
Degradation of monohydroxylated benzoates by strain KUFI-6N of the yeast-like fungus Exophiala jeanselmei.

World J. Microbiol. Biotechnol.
24(2):289-290 (2008)


H. Iwaki, K. Abe, Y. Hasegawa
Isolation and characterization of a new 2,4-dinitrophenol-degrading bacterium Burkholderia sp. strain KU-46 and its degradation pathway.
FEMS Microbiol. Lett. 274(1):112-117 (2007)


H. Iwaki, T.Muraki, S.Ishihara, Y. Hasegawa, K.N.Rankin, T.Sulea, J.Boyd, P.C.K.Lau
Characterization of a Pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis.

J. Bacteriol. 189(9):3502-3514 (2007)
(with cover photograph) この論文のデータが、この論文が掲載された号の表紙に採用されました。

H. Iwaki, Y. HasegawaDegradation of 2-nitrobenzoate by Burkholderia terrae strain KU-15.
Biosci. Biotechnol. Biochem. 71(1):145-151 (2007)

T. Li, H. Iwaki, R. Fu, Y. Hasegawa, H. Zhang, A. Liu
α-Amino-β-carboxymuconic-ε-semialdehyde decarboxylase (ACMSD) is a new member of the amidohydrolase superfamily.
Biochemistry 45(21):6628-6634 (2006)


H. Iwaki, S. Wang, S. Grosse, H. Bergeron, A. Nagahashi, J. Lertvorachon, J. Yang, Y. Konishi, Y. Hasegawa, P.C.K. Lau
Pseudomonad cyclopentadecanone monooxygenase displaying an uncommon spectrum of Baeyer- Villiger oxidations of cyclic ketones.
Appl. Environ. Microbiol. 72(4):2707-2720 (2006)

H. Iwaki, H. Saji, K. Abe, Y. Hasegawa
Cloning and sequence analysis of the 4-hydroxybenzoate 3-hydroxylase gene from a cyclohexanecarboxylate-degrading gram-positive bacterium, "Corynebacterium cyclohexanicum" strain ATCC 51369.

Microbes Environ. 20(3):144-150 (2005)


T. Li, A.L. Waker, H. Iwaki, Y. Hasegawa, A. Liu
Kinetic and spectroscopic characterization of ACMSD from Pseudomonas fluorescens reveals a pentacoordinate mononuclear metallocofactor.
J. Am. Chem. Soc. 127(35):12282-12290 (2005)


H. Iwaki, H. Saji, E. Nakai, Y. Hasegawa
Degradation of cyclopentanol by Trichosporon cutaneum strain KUY-6A.
Microbes Environ. 19(3):241-243 (2004)


S. Wang, M.M. Kayser, H. Iwaki, P.C.K. Lau
Monooxygenase-catalysed Baeyer-Villger oxidations: CHMO versus CPMO.
J. Mol. Cat. B: Enzymatic 22(3-4):211-218 (2003)


T.Muraki, M.Taki, Y.Hasegawa, H.Iwaki, and P.C.K.Lau. 2003.
Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the degradation pathway of 2-nitrobenzoate by Pseudomonas fluorescens strain KU-7. Appl. Enviorn. Microbiol.69(3):1564-1572.


H.Iwaki, Y.Hasegawa, S.Wang, M.M.Kayser, and P.C.K.Lau. 2002.Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. Strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase.Appl. Environ. Microbiol. 68(11):5671-5684

S.Wang, G.Chen, M.M.Kayser, H.Iwaki, P.C.K.Lau, and Y.Hasegawa
Baeyer-Villiger oxidations catalyzed by engineered microorganisms: enantioselective synthesis of
δ-valerolactones with functionalized chains.Can. J. Chem. 80:613-621 (2002).


Y.Hasegawa, Y.Nakai, T.Tokuyama, and H.Iwaki. 2000.Purification and characterization of cyclohexanone 1,2-monooxygenase from Exophiala jeanselmei KUFI-6N.Biosci. Biotechmol. Biochem. 64:2696-2698.

Y.Hasegawa, T.Muraki, T.Tokuyama, H.Iwaki, M.Tatsuno, and P.C.K.Lau. 2000.A novel degradation pathway of 2-nitrobenzoate via 3-hydroxyanthranilate in Pseudomonas fluorescens strain KU-7.FEMS Microbiol. Lett. 190:185-190.

Y.Hasegawa, T.Tokuyama, and H.Iwaki.1999.Cloning and expression of N,N-dimethylformamidase gene from Alcaligenes sp. KUFA-1.Biosci. Biotechnol. Biochem.63:2091-2096.

H.Iwaki, Y.Hasegawa, M.Teraoka, T.Tokuyama, H.Bergeron, and P.C.K.Lau. 1999.Identification of a transcriptional activetor (ChnR) and 6-oxohexanoate dehydrogenase (ChnE) in the cyclohexanol catabolic pathway in Acinetobactersp. NCIMB 9871, and Localization of their encoding genes. Appl. Environ. Microbiol. 65:5158-5162.

H.Iwaki, M.Shimizu, T.Tokuyama, and Y.Hasegawa. 1999.Purification and characterization of a novel cyclohexylamine oxidase from the cyclohexylamine-degrading Brevibacterium IH-35A.J.Biosci.Bioeng. 88:264-268.

H.Iwaki, M.Shimizu, T.Tokuyama, and Y.Hasegawa. 1999.Biodegradation of cyclohexylamine by Brevibacteium oxydans IH-35A.Appl.Enviorn.Microbiol. 65:2322-2334.


総説
細菌によるニトロフェノールとニトロ安息香酸の分解 平成1511月 技苑 No.116, 岩木宏明,長谷川喜衛  1522

国際会議
Broad substrate spectrum and crystal structures of a new Baeyer-Villiger cyclohexanone monooxygenase of Rhodococcus origin. 平成195 90th Canadian Chemistry Conference and Exhibition in Winnipeg, Manitoba,  S. Wang, A. Mirza, B. Yachnin, A. Berghuis, H. Iwaki, Y. Hasegawa, A. Imura, S. Grosse, H. Bergeron, P.C.K. Lau

Biocatalysts and microorganisms as environmental and sustainability tools. 平成161 21世紀COEプログラム「グリーンエネルギー革命による環境再生」 第4回国際シンポジウム, 長岡, P.C.K. Lau, H. Bergeron, J. Boyd, S. Grosse, S.Z. Wang, J.Z. Yang, K. Rankin, T. Sulea, A. Imura, A. Miyadera, H. Iwaki, T. Muraki, Y. Hasegawa

A React-IRTM analysis of lauryl lactone production by cyclododecanone monooxygenas derived from Pseudomonas putida strain HI-70. 平成159 Pseudomonas 2003, Quebec City, Canada, A. Nagahashi, H. Iwaki, Y. Hasegawa, J. Yang, S. Grosse, H. Bergeron, J. Boyd, P.C.K. Lau

Cloning and characterization of the initial 2-nitrobenzoate nitroreductase and 2-hydroxylaminobenzoate mutase encoding genes for 2-nitrobenzoate catabolism in Pseudomonas fluorescens strain KU-7. 平成159 Pseudomonas 2003, Quebec City, Canada, T. Muraki, A. Nagahashi, H. Iwaki, Y. Hasegawa, P.C.K. Lau

A ReactIR study of cyclododecanone monooxygenase-catalyzed reaction for lauryl lactone production.平成155 53rd Annual meeting of the Canadian Society of Microbiologists (CSM), Laval, Canada, J. Yang, H. Iwaki, H. Bergeron, P.C.K. Lau

3-Hydroxyanthranilate 3,4-dioxygenase, a novel eukaryotic homolog in the degradation pathway of 2-nitrobenzoate by Pseudomonas fluorescens strain KU-7. 平成1310ASM conference on Biodegradation, Biotransformation, and Biocatalysis, San Juan, Puerto Rico, T. Muraki, M. Taki, Y. Hasegawa, H. Iwaki, P.C.K. Lau

T.Muraki, M.Taki, Y.Hasegawa, H.Iwaki, amd P.C.K.Lau:
3-Hydroxyanthranilate 3,4-dioxygenase, a novel eukaryotic homolog in the degradation pathway of 2-nitrobenzoate by Pseudomonas fluorescens strain KU-7.
ASM conference of B3, San Juan (2001).

H.Iwaki, Y.Hasegawa, S.Wang, M.Kayser, and P.C.K.Lau:
Cyclopentanone monooxygenase: Old wine, new bottle.
ASM conference of B3, San Juan (2001).

H.Iwaki, Y.Hasegawa and P.C.K.Lau
Biodegradation of cycloaliphatic compounds: New genes and opportunities.
Pseudomonas 2001.

H.Iwaki, Y.Hasegawa, T.Tokuyama, A.Imura, H.Bergeron, and P.C.K.Lau
A fistful of BVMOs (Baeyer-Villiger monooxygenases)

IBC Meeting (2000).


特許(国際)
A gene encoding cyclododecanone monooxygenase. 平成153 WO03025164 EP1430118 CA2460499  H. Iwaki, Y. Hasegawa, P.C.K. Lau

Cloning, sequencing, and expression of a Comamonas cyclopentanone 1,2-monooxygenase encoding gene in Escherichia coli.  平成141 WO0206452 CA2418155  H. Iwaki, Y. Hasegawa, P.C.K. Lau





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